Figure 2

Interactions between a novel cell cycle TF and the other identified cell cycle TFs. The physical or genetic interactions between a novel cell cycle TF ((a) Ash1, (b) Rlm1, (c) Tec1, (d) Stp1, and (e) Ste12) and the other identified cell cycle TFs are shown. Each oval indicates an identified cell cycle TF. A TF name is colored purple if it is a known cell cycle TF but black otherwise. Two ovals are connected by an undirected red line if these two TFs have physical interactions indicated by the current protein-protein interaction data [48]. Two ovals are connected by a directed blue line if the two TFs have genetic interactions indicated by ChIP-chip or/and mutant data [10]. For example, Ace2→Ash1 means that either TF Ace2 binds to the promoter of gene ASH1 or the disruption of TF Ace2 results in a significant change of the expression of gene ASH1.