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Table 7 Evaluation of the Pep-3D-Search's searching capability.

From: Pep-3D-Search: a method for B-cell epitope prediction based on mimotope analysis

Mutation Input sequence TP/PE
   IT = 5000 IT = 10000 IT = 15000 IT = 20000 IT = 25000 IT = 30000
No ESKQKINGNKDMKVLVAAYCQ 19/21 19/21 19/21 19/21 21/21 20/21
10% ESKQR INGNKDMKVLP AAYCQ 19/21 15/21 19/21 18/21 15/21 19/21
15% ESN QKINGNKS MKVLVAAM CQ 16/21 20/21 18/21 16/21 16/21 17/21
20% EN KQKID GNKDC KVLVP AYCQ 18/21 15/21 15/21 15/21 18/21 15/21
25% ESKDR INGNC DMKVH VAAYA Q 17/21 10/21 15/21 10/21 10/21 10/21
30% A SKQKLR GNKN MKVLC AC YCQ 14/21 12/21 14/21 15/21 15/21 14/21
  1. In the test case, the target path of 21 residues in length on the surface of the protein 1g9m (chain G) is E351 S347 K343 Q344 K348 I272 N234 G237 N94 K97 D99 M100 K487 V489 L226 V488 A224 A219 Y217 C218 Q246.
  2. TP: number of true positives; PE: number of residues in the predicted epitope; IT: iteration number of Pep-3D-Search.