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Table 2 Results obtained by various haplotyping software on the experimentally determined ApoE dataset.

From: Shape-IT: new rapid and accurate algorithm for haplotype inference

ApoE

0%MD

5%MD

 

IER

IF

IER

MER

IF

2snp

20.0

83.8

22.7

7.3

83.9

Fastphase

11.3

89.4

17.4

6.1

87.5

Gerbil

20.0

81.3

20.3

6.6

84.6

Ishape

5.6

94.1

10.2

5.9

92.5

Shape-IT

5.6

94.1

10.5

6.2

92.4

Phase v2.1

5.8

94.0

10.2

5.8

92.4

PLEM

12.5

89.8

16.0

6.5

88.7

  1. For the various software tested, we measured the percentage of individuals incorrectly reconstructed (IER), the percentage of missing data incorrectly inferred (MER), and the distance between real and inferred haplotype frequencies (IF) on the ApoE with complete genotypes and 5% random missing genotypes.