Validation with respect to SCOP. Validation of PocketMatch against SCOP. Visualization of (a) the PMS (M1) matrix and (b) the SCOP matrix (M2). Both are square matrices corresponding to 786 proteins illustrating results of all-pair comparisons. In both these a dot indicates the presence of similarity between the given protein-pair and a blank space indicates dis-similarity under the parameters defined (c) Superposition of PMScore (red) and SCOP(blue) matrices using XOR as described in the text. PMScore matrix was computed for 50%-threshold. Corresponding dis-similarity(XOR) and similarity scores are 0.0284 and 0.9716 (d) Plot showing the XOR values for different PMScore matrices varying in threshold from 0 to 100 percent.