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Table 2 Examples of analogy Found in The literature and the Methods used.

From: AnEnPi: identification and annotation of analogous enzymes

EC Enzyme Organism Ref. Method Isocitrate dehydrogenase Escherichia coli/Azotobacter vinelandii [7] a Fructokinase Homo sapiens/Streptococcus mutans [7] a 6-phospho-beta-glucosidase E. coli/H. sapiens [7] a Immunoglobulin A (IgA) proteases Streptococcus sanguis/Neisseria gonorhoeae [27] a
2.1.1.- N-methyltransferase 1 Schizosaccharomyces pombe/Chlamydia pneumoniae/Archaeoglobus fulgidus [9] a, b
2.7.7.- Adenylyltransferase Bacillus subtilis/Saccharomyces cerevisiae [9] a, b Fructose-1,6-bisphosphatase Prochlorococcus marinus/E. coli [28] c
2.3.1.- Enoyl thioester reductase E. coli/Yeast/Rat [29] d Catechol 2,3-dioxygenase Pseudomonas sp./TOL plasmid (pww0) [30] e Glyceric acid 3-phosphate kinase Pisum sativum [31] f Triose phosphate isomerase Pisum sativum [31] f
  1. Table 2: a – computational, b – genetic complementation, c – genome sequencing, d – stereochemical assay, e – biochemical assay and f – isoelectric focusing