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Figure 5 | BMC Bioinformatics

Figure 5

From: Prediction of protein-protein binding site by using core interface residue and support vector machine

Figure 5

The definition of the six local environment classes. This figure shows the classification method of side-chain environment. RASA stands for the relative accessible surface area and FP stands for the fraction of surface area of polar atoms in the surface area of the whole side-chain. If RASA ≥ 0.36, the residue will be divided into class E (exposed). If 0.09 ≤ RASA < 0.36, the residue will be divided into class P (partial buried). Within class P, if FP < 0.67, the residue will be class P1, and if FP ≥ 0.67, the residue will be class P2. If RASA < 0.09, the residue will be divided into class B (buried). In class B, if FP < 0.45, the residue will be class B1, if 0.45 ≤ FP < 0.58, the residue will be class B2, and if FP ≥ 0.58, the residue will be class B3.

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