Influence of sample size on haplotype frequency estimation. A – Similarity index between the frequencies estimated by the computer packages and the real haplotype frequencies. B – Comparison between the number of different haplotypes estimated by the computer packages and the number of haplotypes obtained by segregation. C – Overall difference in haplotype frequencies between estimated and true values. Unbroken line denotes comparisons of Arlequin V3.0 to real data; dotted line, comparisons between PHASE v2.1.1 and real data.