Skip to main content

Advertisement

Table 4 Extended HLA haplotype (5 loci) frequencies above 0.01 determined by direct counting and computational methods (n = 61 individuals)

From: Evaluation of two methods for computational HLA haplotypes inference using a real dataset

  Correct Haplotypes   Haplotype Frequency  
   Real Arlequin V3.0 PHASE V2.1.1
1 A*24-B*27-Cw*02-DQB1*03-DRB1*04 0.033 0.041 0.036
2 A*02-B*27-Cw*01-DQB1*05-DRB1*01 0.033 0.049 0.040
3 A*24-B*27-Cw*01-DQB1*05-DRB1*15 0.025 0.025 0.020
4 A*24-B*27-Cw*02-DQB1*02-DRB1*03 0.025 0.033 0.013
5 A*03-B*27-Cw*02-DQB1*03-DRB1*04 0.025 0.025 0.018
6 A*26-B*27-Cw*02-DQB1*03-DRB1*11 0.025 0.025 0.021
7 A*26-B*52-Cw*12-DQB1*06-DRB1*15 0.016 0.016 0.015
8 A*29-B*44-Cw*16-DQB1*02-DRB1*07 0.016 0.008 0.006
9 A*30-B*35-Cw*06-DQB1*04-DRB1*08 0.016 0.016 -
10 A*24-B*07-Cw*07-DQB1*06-DRB1*15 0.016 - -
11 A*23-B*44-Cw*04-DQB1*02-DRB1*07 0.016 0.016 0.016
12 A*11-B*27-Cw*01-DQB1*05-DRB1*01 0.016 - 0.005
13 A*02-B*27-Cw*02-DQB1*03-DRB1*04 0.016 - 0.014
14 A*02-B*15-Cw*02-DQB1*05-DRB1*10 0.016 0.016 0.016
   I F 0.955 0.952
   I H 0.880 0.923
   MSE 1.3E-05 1.1E-05
  Incorrect Haplotypes    
1 A*01-B*08-Cw*07-DQB1*02-DRB1*03   - 0.015
2 A*02-B*07-Cw*02-DQB1*03-DRB1*04   0.016 -
3 A*02-B*15-Cw*03-DQB1*03-DRB1*01   0.016 -
4 A*02-B*27-Cw*01-DQB1*02-DRB1*07   - 0.011
5 A*02-B*27-Cw*07-DQB1*02-DRB1*03   0.016 -
6 A*03-B*27-Cw*01-DQB1*05-DRB1*01   - 0.015
7 A*03-B*27-Cw*02-DQB1*02-DRB1*07   0.016 0.013
8 A*11-B*14-Cw*08-DQB1*02-DRB1*07   0.016 -
9 A*24-B*35-Cw*04-DQB1*05-DRB1*01   - 0.020
10 A*29-B*27-Cw*02-DQB1*05-DRB1*01   0.016 -
11 A*29-B*27-Cw*16-DQB1*02-DRB1*07   0.016 0.009