Mapping image statistics into 3 dimensions. For each of the 502 sub-cellular localization images, Haralick statistics and TAS measures are generated. The statistics vectors for the image set are Sammon mapped into 3 dimensions and visualized as shown with a sphere for each image. Each color represents a different sub-cellular localization. Each sub-cellular localization clusters well under the mapping, though there is some spatial overlap between classes such as mitochondria and endoplasmic reticulum. See also Additional file 1.