Figure 5

Chromosomal ideogram representation. An ISCN ideogram of the mouse X chromosome is shown (column 1). The chromosomal localization of genes in the DET-MI expression cluster is marked by red (plus or top DNA strand) and blue (minus or bottom DNA strand) lines (column 2). A color coded heat map (see scale bar in Figure 3) shows expression signals for each sample (column 3). The numbers of mapped genes within consecutive regions of 10 Mbp are plotted on the X- and Y-axes, respectively (column 4). Color coded bars show the numbers of observed loci with red and blue indicating over- or under-representation. Grey bars represent the number of loci falling into a given region by chance. Red arrows mark regions that are enriched in loci (FDR-adjusted p-value < 0.001). The remaining columns 5–7 show that the X-chromosome is devoid of meiotic genes falling into the DET-ME cluster.