Table 2 Tight Cluster Results 1

BC-Pelp1_Modulation_of_Estrogen_Receptor

15.38

20

Alzheimer's_disease

17.13

23

BC-Deregulation_of_CDK5_in_Alzheimers_Disease

16.08

24

BC-Downregulated_of_MTA_3_in_ER_negative_Breast_Tumors

12.24

26

BC-GATA3_participate_in_activating_the_Th2_cytokine

11.89

33

Nitrogen_metabolism

14.34

40

Gene Symbols of informative genes in this pathway cluster

MAPK3, PELP1, ESR1, PDZK1, HSPB1, CA12, GLS, IL5, JUNB, GATA3, MAP2K3, MAPT, STH, CSNK1A1

p 53 (A3i in Additional file 1)

BC-Pelp1_Modulation_of_Estrogen_Receptor

13.94

20

BC-Downregulated_of_MTA_3_in_ER_negative_Breast_Tumors_

15.54

26

BC-GATA3_participate_in_activating_the_Th2_cytokine

13.55

33

Nitrogen_metabolism

17.13

40

BC-CARM1_and_Regulation_of_the_Estrogen_Receptor

14.34

54

Gene Symbols of informative genes in this pathway cluster

MAPK3, PELP1, ESR1, PDZK1, HSPB1, HDAC2, CA12, GLS, IL5, JUNB, GATA3, MAP2K3