Building pathway clusters from Random Forests classification using class votes

BMC Bioinformatics

Table 8 Shortest Path between CA12 and other Genes in the Top 22 Pathways (without overlap with Nitrogen Metabolism pathway)

CA12 and	Distance (gene steps)	Number of links with the shortest distance*	Genes with literature related to breast cancer*
ESR1 (in pathway cluster)	3	1 (HIF-1, NCOA1)	4
EGFR	3	4 (HIF-1 + MAPK3, Beta-catenin, STAT5B, MAPK1)	6
IL6ST	3	2 (HIF-1 + MAPK1, MPAK3)	3
COX7c	4
IGF1R	4
YES	4
ACTIN1	5
PRKX	5
VAV3	5
ABAT	6
HMGCL	6
SSH3	6
TARS	6
ADCY9	7
BBOX1	7
PDXK	7
UQCRH	7
B3GNT6	9
DAZAP2	Infinity

ISSN: 1471-2105