Using neural networks and evolutionary information in decoy discrimination for protein tertiary structure prediction

Table 7 Top model selection: P-values of one-tailed Wilcoxon sign-rank test between the SP-NN-dist, SP-NN-solvpair, SP-NN-solvpairndist methods and the corresponding basic NN methods

Decoy Dataset	SP-NN-dist			SP-NN-solvpair			SP-NN-solvpairndist
	NN-dist			NN-solvpair			NN-solvpairndist
	TM-score	GDT-TS	MaxSub	TM-score	GDT-TS	MaxSub	TM-score	GDT-TS	MaxSub
4state_reduced	0.1562	0.1562	0.1562	0.0938	0.0938	0.0938	0.1562	0.1562	0.1562
Baker	0.8474	0.8743	0.6553	0.0430	0.0430	0.0727	0.0366	0.0337	0.0502
fisa_casp3	0.0625	0.0625	0.0625	0.5625	0.5625	0.3125	0.5	0.5	0.5
fisa	0.5	0.625	0.625	0.5	0.5	0.5	0.625	0.5	0.625
lattice_ssfit	0.3711	0.7266	0.5	0.1875	0.5312	0.0781	0.1914	0.7266	0.1562
lmds	0.9863	0.9941	0.9512	0.7695	0.3711	0.6289	0.7871	0.2852	0.8496
lmds_v2	0.2158	0.2783	0.5449	0.2891	0.3438	0.4219	0.918	0.8984	0.8203
semfold	0.8906	0.9219	0.9219	0.3125	0.3125	0.1875	0.9375	0.5	0.8438
All	0.7256	0.8031	0.6942	0.0651	0.0258	0.0370	0.2048	0.0926	0.1966
αβ	0.2877	0.574	0.8428	0.1906	0.8863	0.2507	0.9781	0.9886	0.956
α-only	0.8408	0.8895	0.7858	0.0614	0.0185	0.0432	0.0438	0.0115	0.0490
β-only	0.3438	0.6562	0.0781	0.1562	0.1562	0.6289	0.1562	0.1562	0.6289

ISSN: 1471-2105