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Figure 4 | BMC Bioinformatics

Figure 4

From: Modeling Escherichia coli signal peptidase complex with bound substrate: determinants in the mature peptide influencing signal peptide cleavage

Figure 4

Superimposition of DsbA 13–25 precursor protein with lipopeptide and β-lactam inhibitors. A model of the DsbA 13–25 precursor protein (red) bound to the active site of E. coli type 1 SPase (grey). Superimposition of the P7 to P1' positions of DsbA precursor protein with the lipopeptide (blue; PDB ID: 1T7D) and β-lactam (yellow; PDB ID: 1B12) inhibitors from A, top view and B, side view respectively. Residues N-terminal to P7 and C-terminal to P2' have been truncated for clarity.

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BMC Bioinformatics

ISSN: 1471-2105

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