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Table 1 Operating characteristics in simulation study of ρ = 0.1, 0.5 and 0.9.

From: Multivariate hierarchical Bayesian model for differential gene expression analysis in microarray experiments

Corr. Coef. Method Sensitivity Specificity PPV NPV FDR
0.1 GLRT 0.742 0.998 0.960 0.987 0.040
  LNN 0.667 0.991 0.826 0.980 0.174
  t-test 0.557 0.987 0.692 0.978 0.308
  fold change 0.309 0.999 0.968 0.966 0.032
0.5 GLRT 0.945 0.998 0.966 0.997 0.034
  LNN 0.635 0.986 0.873 0.972 0.127
  t-test 0.516 0.968 0.435 0.977 0.565
  fold-change 0.252 1 1 0.966 0
0.9 GLRT 0.980 0.999 0.990 0.999 0.010
  LNN 0.568 0.988 0.877 0.987 0.123
  t-test 0.406 0.972 0.436 0.969 0.564
  fold change 0.139 1 1 0.956 0