Skip to main content

Table 3 Contributions of model organisms to human theoretical and experimental interologs.

From: Ortholog-based protein-protein interaction prediction and its application to inter-species interactions

Species (Taxonomy ID)

Theoretical Interologs Coveragea

Experimental PPIs and Interologsb

 

HomoloGene

OrthoMCL

TIGR EGO

All Available PPIs

Confident PPIs

 

IC HSA

IC HSA

IC HSA

Interologs

IC HSA

C SP

Interologs

IC HSA

C SP

H. sapiens (9606)

94.86%

100.00%

95.78%

3859

8.72%

N/A

1316

4.61%

N/A

M. musculus (10090)

70.19%

77.56%

50.24%

1662

3.76%

43.07%

551

1.93%

41.86%

R. norvegicus (10116)

60.14%

71.59%

35.83%

480

1.08%

12.44%

251

0.88%

19.07%

D. melanogaster (7227)

6.68%

12.01%

4.79%

766

1.73%

19.85%

92

0.32%

7.00%

C. elegans (6239)

4.11%

8.05%

2.78%

231

0.52%

5.99%

29

0.10%

2.20%

S. cerevisiae (4932)

0.67%

2.02%

0.77%

766

1.73%

19.85%

425

1.49%

32.29%

  1. aICHSA for theoretical interologs are the number of interologs divided by all theoretical human PPIs derived from each ortholog databases.
  2. b ICHSA for all available and confident experimental interologs are the number of interologs divided by available and confident human PPIs.