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Table 3 Contributions of model organisms to human theoretical and experimental interologs.

From: Ortholog-based protein-protein interaction prediction and its application to inter-species interactions

Species (Taxonomy ID) Theoretical Interologs Coveragea Experimental PPIs and Interologsb
  HomoloGene OrthoMCL TIGR EGO All Available PPIs Confident PPIs
  IC HSA IC HSA IC HSA Interologs IC HSA C SP Interologs IC HSA C SP
H. sapiens (9606) 94.86% 100.00% 95.78% 3859 8.72% N/A 1316 4.61% N/A
M. musculus (10090) 70.19% 77.56% 50.24% 1662 3.76% 43.07% 551 1.93% 41.86%
R. norvegicus (10116) 60.14% 71.59% 35.83% 480 1.08% 12.44% 251 0.88% 19.07%
D. melanogaster (7227) 6.68% 12.01% 4.79% 766 1.73% 19.85% 92 0.32% 7.00%
C. elegans (6239) 4.11% 8.05% 2.78% 231 0.52% 5.99% 29 0.10% 2.20%
S. cerevisiae (4932) 0.67% 2.02% 0.77% 766 1.73% 19.85% 425 1.49% 32.29%
  1. aICHSA for theoretical interologs are the number of interologs divided by all theoretical human PPIs derived from each ortholog databases.
  2. b ICHSA for all available and confident experimental interologs are the number of interologs divided by available and confident human PPIs.