From: The value of position-specific scoring matrices for assessment of protein allegenicity
Method | E-value threshold | FN | FP | ACC (%) | SP (%) | SE (%) | PPV (%) | NPV (%) | MCC |
---|---|---|---|---|---|---|---|---|---|
General Profile | 10 | 11 | 1792 | 21.67 | 10.38 | 96.42 | 13.99 | 94.71 | 0.08 |
 | 1 | 22 | 737 | 67.03 | 63.17 | 92.58 | 27.74 | 98.25 | 0.38 |
 | 10-1 | 31 | 298 | 85.72 | 85.11 | 89.80 | 48.45 | 98.22 | 0.59 |
 | 10-2 | 36 | 184 | 90.42 | 90.80 | 87.95 | 60.22 | 98.03 | 0.68 |
 | 10-3 | 41 | 137 | 92.27 | 93.14 | 86.56 | 66.70 | 97.87 | 0.72 |
 | 10-4 | 43 | 108 | 93.44 | 94.61 | 85.70 | 71.76 | 97.77 | 0.75 |
 | 10-6 | 48 | 83 | 94.32 | 95.87 | 84.04 | 76.53 | 97.55 | 0.77 |
 | 10-9 | 53 | 62 | 95.02 | 96.92 | 82.45 | 81.34 | 97.34 | 0.79 |
Group-Specific | 10 | 14 | 1801 | 21.14 | 9.92 | 95.43 | 13.79 | 93.48 | 0.06 |
Profiles | 1 | 22 | 748 | 66.53 | 62.58 | 92.72 | 27.33 | 98.27 | 0.38 |
 | 10-1 | 29 | 317 | 84.99 | 84.17 | 90.40 | 46.88 | 98.31 | 0.58 |
 | 10-2 | 34 | 202 | 89.76 | 89.89 | 88.87 | 57.87 | 98.16 | 0.66 |
 | 10-3 | 37 | 151 | 91.83 | 92.44 | 87.81 | 64.73 | 98.04 | 0.71 |
 | 10-4 | 40 | 124 | 92.86 | 93.79 | 86.69 | 68.87 | 97.90 | 0.73 |
 | 10-6 | 44 | 94 | 94.02 | 95.31 | 85.50 | 74.51 | 97.75 | 0.76 |
 | 10-9 | 48 | 70 | 94.88 | 96.52 | 84.04 | 79.49 | 97.56 | 0.79 |