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Table 3 Results of the similarity analyses between clustered miRNAs and other sequences.

From: Filtering of false positive microRNA candidates by a clustering-based approach

Genome   T-COFFEE sequence alignment score RNAdistance structure alignment score
Human Category Maximum Average Minimum Std Dev Maximum Average Minimum Std Dev
  (i) 79 45.20 17 15.70 71 28.86 0 9.73
  (ii) 73 46.30 15 12.96 94 37.21 15 11.29
  (iii) 74 45.47 17 14.13 203 140.89 104 18.78
  (iv) 77 44.81 15 12.60 134 75.55 28 22.19
Mouse (i) 79 43.63 0 14.40 72 30.41 0 9.33
  (ii) 78 45.28 16 13.03 69 35.19 10 9.67
  (iii) 75 43.72 16 14.40 239 139.93 103 17.31
  (iv) 72 45.37 15 13.33 128 69.55 26 19.31
Rat (i) 75 44.28 17 12.83 113 31.41 11 12.60
  (ii) 72 45.18 16 13.12 116 35.68 13 11.73
  (iii) 69 45.03 16 12.48 198 143.12 110 18.43
  (iv) 73 47.90 15 13.26 114 74.69 32 18.74
  1. Sequence and secondary structural alignments are performed for each clustered miRNA with sequences from the following categories: (i) clustered miRNAs, (ii) non-clustered miRNAs, (iii) random and (iv) neighboring sequences. A higher score implies a greater distance and hence a higher degree of dissimilarity. Std Dev, standard deviation.