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Table 5 Results of our clustering-based approach on the human, mouse and rat genome data.

From: Filtering of false positive microRNA candidates by a clustering-based approach

  Human Mouse (All) Mouse (Distinct) Rat
# of predictions 374 381 359 276
# of TPs 196 172 165 101
# of real miRNAs 240 245 212 146
SE 81.67% 70.20% 77.83% 69.18%
Change in SE -7.91% -11.02% -8.09% -17.81%
PPV 52.41% 45.14% 45.96% 36.59%
Change in PPV +21.25% +14.81% +17.37% +15.94%
  1. This table shows the SE and PPV obtained after our filtering approach is applied to the predicted candidates generated by ProMirII-g. The PPV is increased by more than 15% in all the three genomes. The SE is kept reasonably high as it is just slightly decreased by a percentage less than 10% in the human and mouse genomes.