Skip to main content

Table 4 A comparison between MiRTif and three ab initio target predicting software programs, PicTar, miRBase and TargetScan using miR-224, which was discovered to be significantly up-regulated in hepatocellular carcinoma patients.

From: MiRTif: a support vector machine-based microRNA target interaction filter

Gene Entrez Gene ID Gene description PicTar ranking miRBase ranking TargetScan ranking MiRTif
H3F3B 3021 H3 histone, family 3B (H3.3B) 1 na 122 +1.69
API5 8539 Apoptosis inhibitor 5 2 na 99 +1.32
ARMCX2 9823 Armadillo repeat containing, X-linked 2 4 198 na -0.98
CDK9 1025 Cyclin-dependent kinase 9 (CDC2-related kinase) 9 25 na -0.15
NCOA6 23054 Nuclear receptor coactivator 6 10 204 47 +0.94
ATF2 1386 Activating transcription factor 2 64 19 104 +1.27
NUP153 9972 nucleoporin 153 kDa 168 1 46 -1.46
FOSB 2354 FBJ murine osteosarcoma viral Nncogene homolog B 222 4 125 +0.11
  1. Ranking indicates the rank predicted by respective software program. "NA" indicates that the particular program did not produce an interaction between the corresponding target gene and miR-224. For the discriminant scores under MiRTif, positive scores indicate true predictions while negative scores negative predictions. The score is proportional to the sample's distance from the hyperplane. So a large positive value implies high confidence that the sample lies in the positive class.