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Table 4 Selected miRNAs associated with human cancers

From: Finding microRNA regulatory modules in human genome using rule induction

miRNA

Function

Type of cancer

References

hsa-miR-143

Tumor suppressor

Colorectal, colon and breast cancer

[24]

hsa-miR-27b

Tumor suppressor

Colon cancer

[25]

hsa-miR-145

Tumor suppressor

Breast cancer

[24, 28]

hsa-miR-125b

Tumor suppressor

Breast cancer, Hodgkin lymphoma

[28, 40]

hsa-miR-155

Oncogene

Breast colon, and lung cancer

[28, 41]

hsa-miR-17-5p

Oncogene

MYC, Lung cancer and B-cell lymphomas

[42]

hsa-miR-15a

Tumor suppressor

B-cell chronic lymphocytic leukemia

[43]

hsa-miR-221

Tumor suppressor

Papillary thyroid carcinoma, lung cancer

[40, 42, 44]

hsa-miR-181b

Tumor suppressor

Colorectal and colon cancer

[25, 45, 46]

hsa-miR-19a

Tumor suppressor

B-cell lymphoma

[42]

hsa-miR-200c

Tumor suppressor

Papillary thyroid carcinoma, B-cell lymphoma, colorectal cancer

[42, 46]

hsa-miR-222

Oncogene

Papillary thyroid carcinoma

[42]

hsa-miR-146

Oncogene

Papillary thyroid carcinoma, breast cancer

[41, 42]

hsa-miR-26a

Tumor suppressor

Colorectal cancer

[46]

hsa-miR-25

Tumor suppressor

Conlon cancer

[25, 41]

hsa-miR-181a

Unknown

Acute myeloid leukaemia

[47]

hsa-miR-126

Tumor suppressor

Breast cancer metastasis

[48]

hsa-let-7d/e

Tumor suppressor

Lung cancer

[49]

hsa-miR-27a

Oncogene

Breast cancer

[50]

hsa-miR-125a

Tumor suppressor

Breast cancer

[28]

  1. Several miRNAs in our module set were confirmed to be related to human cancers (including breast, lung, colon, and colorectal cancer).