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Figure 5 | BMC Bioinformatics

Figure 5

From: A three-state prediction of single point mutations on protein stability changes

Figure 5

ROC curves for the structure-based predictor. The cross-validation True Positive Rate (TPR) versus the False Positive Rate (FPR) are plotted the best method (SVM-3DR9) and for the baseline method (SVM-BASE). In part (A) the ROC curves of the two methods are relative to the prediction of increasing and decreasing free energy mutations (|ΔΔG|>1.0 kcal/mole), while in part (B) they are calculated for neutral mutations (|ΔΔG|≤1.0 kcal/mole).

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