Figure 2

Kringle tip contacts with αIIbβ3 in open conformation. The α and β chains of αIIbβ3 are shown as pale pink and yellow spheres, respectively. The amino acids stretch homologous to the α325 peptide is in magenta, homology to β1P1 is in orange, homology to β1P2 in yellow. Res 113-123 are shown as cartoons, those corresponding to the second ranking solution are in red, those corresponding to the third ranking solution are in green, those corresponding to the fourth ranking solution are in blue and those corresponding to the fifth ranking solution are in cyan.