From: New challenges for text mining: mapping between text and manually curated pathways
class | example | inferred reaction IDs | ||
---|---|---|---|---|
1 | a | ex1 | p50 is translated as a precursor of 105 kDa. | R10 |
b | ex2 | CD23-induced NF-kappaB is a heterodimer composed of p65/p50 subunits. | R1 | |
2 | a | ex3 | RelA contains a high-affinity binding site for its cytoplasmic inhibitor, I kappa B alpha. | R2 |
b | ex4 | I kappa B-alpha inhibits transcription factor NF-kappa B by retaining it in the cytoplasm. | R2 | |
3 | a | ex5 | When either serine- 32 or serine- 36 of I kappa B-alpha was mutated, the protein did not undergo signal-induced phosphorylation. | R3 |
b | ex6 | Pretreatment of the cells with the proteasome inhibitor N-Ac-Leu-Leu-norleucinal inhibits this ligand-induced degradation of the human I kappa B alpha protein. | R5 | |
4 | ex7 | As observed with I kappa B alpha, nuclear RelA stimulates p100 mRNA and protein expression. | R8 | |
5 | ex8 | Nuclear expression of NF-kappa B occurs after its induced dissociation from its cytoplasmic inhibitor I kappa B alpha. | R2 | |
6 | ex9 | A failure to degrade IkappaB-alpha pretreated with PAO is not due to its inhibitory effect on proteasomal degradation. | R5 |