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Table 2 The major properties of molecular event objects in OWL-DL.

From: Drug interaction prediction using ontology-driven hypothetical assertion framework for pathway generation followed by numerical simulation

Properties Domain (class) Range (class)
oboRel:relationship Process, Continuant Process, Continuant
-oboRel:located in independent_entities Independent_entities, fma:Anatomical_cavity
-oboRel:has_participant Process Independent_entities
-- hasResultantParticipant Process Independent_entities
-- hasTriggerParticipant Process Independent_entities
-- hasSituatedParticipant Process Independent_entities
hasSubProcesses Process Process
occurred_in Process Independent_entities, fma:Anatomical_cavity
  1. The relations among molecular events, attributes (continuants) and drug interactions shown in Figure 2 were implemented as OWL properties. We defined five properties for implementing molecular event objects in OWL-DL in addition to the properties of OBO Relation ontology. Three properties for resultant, trigger, and situated participants were defined as sub properties of oboRel:has_participant, inheriting the definition of the super property. Note that classes for Domain and Range of properties are denoted by the controlled vocabulary defined in Figure 3.