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Table 6 Parameters for drug interactions and drug administrations.

From: Drug interaction prediction using ontology-driven hypothetical assertion framework for pathway generation followed by numerical simulation

Parameters

Values

Ki APC

1.40 * 10-3

Ki NPC

5.94 * 10-4

ka KCZ [min-1]

1.83 * 10-2

dose Irinotecan [nmol/kg]

4.86 * 103

tdose,Irinotecan[min]

90

dose KCZ [nmol/kg]

5.16 * 103

  1. Ki APC and Ki NPC were calculated from the experimental data reported by Haaz et al. [25,26]. ka KCZ was obtained the from published paper [29].