TY - JOUR AU - Shi, Leming AU - Jones, Wendell D. AU - Jensen, Roderick V. AU - Harris, Stephen C. AU - Perkins, Roger G. AU - Goodsaid, Federico M. AU - Guo, Lei AU - Croner, Lisa J. AU - Boysen, Cecilie AU - Fang, Hong AU - Qian, Feng AU - Amur, Shashi AU - Bao, Wenjun AU - Barbacioru, Catalin C. AU - Bertholet, Vincent AU - Cao, Xiaoxi Megan AU - Chu, Tzu-Ming AU - Collins, Patrick J. AU - Fan, Xiao-hui AU - Frueh, Felix W. AU - Fuscoe, James C. AU - Guo, Xu AU - Han, Jing AU - Herman, Damir AU - Hong, Huixiao AU - Kawasaki, Ernest S. AU - Li, Quan-Zhen AU - Luo, Yuling AU - Ma, Yunqing AU - Mei, Nan AU - Peterson, Ron L. AU - Puri, Raj K. AU - Shippy, Richard AU - Su, Zhenqiang AU - Sun, Yongming Andrew AU - Sun, Hongmei AU - Thorn, Brett AU - Turpaz, Yaron AU - Wang, Charles AU - Wang, Sue Jane AU - Warrington, Janet A. AU - Willey, James C. AU - Wu, Jie AU - Xie, Qian AU - Zhang, Liang AU - Zhang, Lu AU - Zhong, Sheng AU - Wolfinger, Russell D. AU - Tong, Weida PY - 2008 DA - 2008/08/12 TI - The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies JO - BMC Bioinformatics SP - S10 VL - 9 IS - 9 AB - Reproducibility is a fundamental requirement in scientific experiments. Some recent publications have claimed that microarrays are unreliable because lists of differentially expressed genes (DEGs) are not reproducible in similar experiments. Meanwhile, new statistical methods for identifying DEGs continue to appear in the scientific literature. The resultant variety of existing and emerging methods exacerbates confusion and continuing debate in the microarray community on the appropriate choice of methods for identifying reliable DEG lists. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-9-S9-S10 DO - 10.1186/1471-2105-9-S9-S10 ID - Shi2008 ER -