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Figure 4 | BMC Bioinformatics

Figure 4

From: The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies

Figure 4

Concordance for cross-platform comparisons. Panel a: Based on the data set of "12,091" genes (without noise filtering); Panel b: Based on subsets of genes commonly detected ("Present") by two platforms. For each platform, the data from test site1 are used for cross-platform comparison. Each POG line corresponds to comparison of the DEGs from two microarray platforms using one of the six gene selection methods. There are ten platform-platform comparison pairs, resulting in 60 POG lines for each panel. The x-axis represents the number of selected DEGs, and the y-axis is the percentage (%) of genes common to the two gene lists derived from two platforms at a given number of DEGs. POG lines circled by the blue oval are from FC based gene selection methods with or without a P cutoff, whereas POG lines circled by the teal oval are from P based gene selection methods with or without an FC cutoff. Shown here are results for comparing sample B and sample A.

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