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Figure 8 | BMC Bioinformatics

Figure 8

From: An iterative block-shifting approach to retention time alignment that preserves the shape and area of gas chromatography-mass spectrometry peaks

Figure 8

A comparison of retention-time alignment by three methods. Top panel: Unabridged total-ion-current (TIC) chromatograms for 45 analytical runs in a GC-MS metabolomics experiment, prior to alignment. Remaining panels: columns 1–4 show details for peaks labelled 1–4 in the top panel, both unaligned (top row), and aligned using COW [17] with automated parameter selection [26], using XCMS with three iterations [8], and using iterative block-shifting with its default parameters, as described in the text (rows 2–4, respectively).

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