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Table 1 Top-10 SCAN clusters with highest p-values

From: A structural approach for finding functional modules from large biological networks

  Cluster ID P -value GO Term Term Freq. in Network Term Freq. in Cluster Cluster Size
Biological Process 1 4.45E-98 nuclear mrna splicing, via spliceosome 66 58 88
  89 1.01E-65 translation 252 58 64
  5 1.16E-52 ubiquitin-dependent protein catabolic process 60 34 56
  2 9.04E-40 transcription from rna polymerase ii promoter 50 41 288
  15 8.58E-38 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 13 13 13
  22 1.36E-30 chromatin remodeling 46 20 40
  192 5.46E-29 vacuolar acidification 23 13 16
  13 6.36E-29 chromosome segregation 36 16 25
  24 2.14E-28 regulation of microtubule polymerization or depolymerization 10 10 12
  30 9.29E-28 regulation of cell growth 10 10 13
Cellular Components 7 6.81E-53 cytosolic large ribosomal subunit 80 55 222
  89 1.50E-51 mitochondrial small ribosomal subunit 33 29 64
  1 2.53E-41 u4/u6 × u5 tri-snrnp complex 27 25 88
  15 9.01E-36 anaphase-promoting complex 15 13 13
  22 7.15E-31 rsc complex 16 15 40
  24 2.14E-28 dash complex 10 10 12
  38 2.14E-28 trapp complex 10 10 12
  185 7.18E-26 ribonuclease mrp complex 9 9 11
  155 5.84E-25 smc5-smc6 complex 8 8 8
  53 4.93E-24 dna replication preinitiation complex 21 12 22
Molecular Functions 89 5.64E-71 structural constituent of ribosome 210 58 64
  5 2.75E-45 endopeptidase activity 26 24 56
  1 7.12E-45 contributes_to rna splicing factor activity, transesterification mechanism 29 27 88
  37 6.44E-41 snap receptor activity 24 23 74
  192 4.65E-28 hydrogen ion transporting atpase activity, rotational mechanism 12 11 16
  185 7.18E-26 contributes_to ribonuclease mrp activity 9 9 11
  22 6.60E-23 contributes_to dna-dependent atpase activity 15 12 40
  34 1.30E-22 protein transporter activity 24 14 46
  15 2.25E-18 ubiquitin-protein ligase activity 44 10 13
  8 1.37E-17 dolichyl-diphosphooligosaccharide-protein glycotransferase activity 8 8 35