Skip to main content

Table 2 Top-10 CNM clusters with highest p-values

From: A structural approach for finding functional modules from large biological networks

  Cluster ID P -value GO Term Term Freq. in Network Term Freq. in Cluster Cluster Size
Biological Process 15 2.10E-61 nuclear mrna splicing, via spliceosome 66 55 220
  17 5.00E-40 transposition, rna-mediated 33 19 22
  13 5.11E-31 rna elongation from rna polymerase ii promoter 53 51 919
  49 4.30E-25 ribosomal large subunit assembly and maintenance 39 34 549
  16 1.09E-23 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 13 13 75
  58 2.78E-22 microtubule nucleation 22 16 98
  53 7.86E-20 trna processing 14 8 10
  45 8.35E-18 negative regulation of gluconeogenesis 9 7 12
  56 3.15E-17 ubiquitin-dependent protein catabolic process via the multivesicular body pathway 13 11 91
  63 1.73E-13 mrna polyadenylation 17 13 241
Cellular Components 11 3.67E-66 mitochondrial large ribosomal subunit 43 41 107
  49 4.72E-42 cytosolic large ribosomal subunit 80 64 549
  17 5.00E-40 retrotransposon nucleocapsid 33 19 22
  58 1.28E-30 condensed nuclear chromosome kinetochore 30 22 98
  16 2.48E-24 anaphase-promoting complex 15 14 75
  20 1.58E-23 peroxisomal membrane 12 9 11
  37 9.63E-23 smc5-smc6 complex 8 8 11
  53 2.36E-22 ribonuclease mrp complex 9 8 10
  63 5.21E-18 mrna cleavage and polyadenylation specificity factor complex 14 14 241
  65 3.13E-15 alpha-1,6-mannosyltransferase complex 6 6 18
Molecular Functions 17 1.71E-26 rna binding 130 19 22
  58 2.34E-24 structural constituent of cytoskeleton 47 22 98
  53 2.36E-22 contributes_to ribonuclease mrp activity 9 8 10
  13 9.16E-19 dna-directed rna polymerase activity 31 30 919
  49 6.52E-17 snorna binding 21 20 549
  48 5.97E-13 contributes_to protein transporter activity 7 5 10
  30 1.24E-10 nad-independent histone deacetylase activity 4 4 15
  65 2.79E-10 contributes_to alpha-1,6-mannosyltransferase activity 4 4 18
  33 1.34E-09 endopeptidase activity 26 24 1408
  63 2.52E-09 contributes_to histone lysine n-methyltransferase activity (h3-k4 specific) 7 7 241