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Figure 6 | BMC Bioinformatics

Figure 6

From: From microarray to biology: an integrated experimental, statistical and in silico analysis of how the extracellular matrix modulates the phenotype of cancer cells

Figure 6

Transcription factor activity identified in silico and in vivo. A) Example of TREs overrepresented in first ontological cluster. Several genes (vertical) share common TREs (horizontal), highlighted by red. Results were filtered to show only TREs overrepresented at p < 0.05 and FDR < 0.3. TREs in bold show a significant increase in expression on crECM compared to plastic confirmed by transcription factor array experiment. B) Example of changes in binding activity of a few TFs on plastic and crECM. Gray/black bars show binding activity on plastic/crECM, respectively.

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