TY - JOUR AU - Onn, A. AU - Fidler, I. J. PY - 2002 DA - 2002// TI - Metastatic potential of human neoplasms JO - In Vivo VL - 16 ID - Onn2002 ER - TY - JOUR AU - Fidler, I. J. PY - 2003 DA - 2003// TI - The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited JO - Nat Rev Cancer VL - 3 UR - https://doi.org/10.1038/nrc1098 DO - 10.1038/nrc1098 ID - Fidler2003 ER - TY - JOUR AU - Fidler, I. J. AU - Kripke, M. L. PY - 1977 DA - 1977// TI - Metastasis results from preexisting variant cells within a malignant tumor JO - Science VL - 197 UR - https://doi.org/10.1126/science.887927 DO - 10.1126/science.887927 ID - Fidler1977 ER - TY - JOUR AU - Liu, R. AU - Wang, X. AU - Chen, G. Y. AU - Dalerba, P. AU - Gurney, A. AU - Hoey, T. AU - Sherlock, G. AU - Lewicki, J. AU - Shedden, K. AU - Clarke, M. F. PY - 2007 DA - 2007// TI - The prognostic role of a gene signature from tumorigenic breast-cancer cells JO - N Engl J Med VL - 356 UR - https://doi.org/10.1056/NEJMoa063994 DO - 10.1056/NEJMoa063994 ID - Liu2007 ER - TY - JOUR AU - Parker, B. AU - Sukumar, S. PY - 2003 DA - 2003// TI - Distant metastasis in breast cancer: molecular mechanisms and therapeutic targets JO - Cancer Biol Ther VL - 2 UR - https://doi.org/10.4161/cbt.188 DO - 10.4161/cbt.188 ID - Parker2003 ER - TY - JOUR AU - Provenzani, A. AU - Fronza, R. AU - Loreni, F. AU - Pascale, A. AU - Amadio, M. AU - Quattrone, A. PY - 2006 DA - 2006// TI - Global alterations in mRNA polysomal recruitment in a cell model of colorectal cancer progression to metastasis JO - Carcinogenesis VL - 27 UR - https://doi.org/10.1093/carcin/bgi377 DO - 10.1093/carcin/bgi377 ID - Provenzani2006 ER - TY - JOUR AU - Ramaswamy, S. AU - Ross, K. N. AU - Lander, E. S. AU - Golub, T. R. PY - 2003 DA - 2003// TI - A molecular signature of metastasis in primary solid tumors JO - Nat Genet VL - 33 UR - https://doi.org/10.1038/ng1060 DO - 10.1038/ng1060 ID - Ramaswamy2003 ER - TY - JOUR AU - van 't Veer, L. J. AU - Dai, H. AU - Vijver, M. J. v. a. n. d. e. AU - He, Y. D. AU - Hart, A. A. AU - Mao, M. AU - Peterse, H. L. AU - Kooy, K. v. a. n. d. e. r. AU - Marton, M. J. AU - Witteveen, A. T. PY - 2002 DA - 2002// TI - Gene expression profiling predicts clinical outcome of breast cancer JO - Nature VL - 415 UR - https://doi.org/10.1038/415530a DO - 10.1038/415530a ID - van 't Veer2002 ER - TY - JOUR AU - Fidler, I. J. PY - 1995 DA - 1995// TI - Modulation of the organ microenvironment for treatment of cancer metastasis JO - J Natl Cancer Inst VL - 87 UR - https://doi.org/10.1093/jnci/87.21.1588 DO - 10.1093/jnci/87.21.1588 ID - Fidler1995 ER - TY - JOUR AU - Hunter, K. PY - 2006 DA - 2006// TI - Host genetics influence tumour metastasis JO - Nat Rev Cancer VL - 6 UR - https://doi.org/10.1038/nrc1803 DO - 10.1038/nrc1803 ID - Hunter2006 ER - TY - JOUR AU - Crawford, N. P. AU - Hunter, K. W. PY - 2006 DA - 2006// TI - New perspectives on hereditary influences in metastatic progression JO - Trends Genet VL - 22 UR - https://doi.org/10.1016/j.tig.2006.07.009 DO - 10.1016/j.tig.2006.07.009 ID - Crawford2006 ER - TY - JOUR AU - LaTulippe, E. AU - Satagopan, J. AU - Smith, A. AU - Scher, H. AU - Scardino, P. AU - Reuter, V. AU - Gerald, W. L. PY - 2002 DA - 2002// TI - Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease JO - Cancer Res VL - 62 ID - LaTulippe2002 ER - TY - JOUR AU - Scher, H. I. AU - Heller, G. PY - 2000 DA - 2000// TI - Clinical states in prostate cancer: toward a dynamic model of disease progression JO - Urology VL - 55 UR - https://doi.org/10.1016/S0090-4295(99)00471-9 DO - 10.1016/S0090-4295(99)00471-9 ID - Scher2000 ER - TY - CHAP AU - Fidler, I. J. ED - DeVita, V. T. ED - Hellman, S. ED - Rosenberg, S. A. PY - 1997 DA - 1997// TI - Molecular biology of cancer: invasion and metastasis BT - Cancer Principles and Practice of Oncology PB - Lippincott-Raven CY - Philadelphia ID - Fidler1997 ER - TY - JOUR AU - Draghici, S. AU - Khatri, P. AU - Martins, R. P. AU - Ostermeier, G. C. AU - Krawetz, S. A. PY - 2003 DA - 2003// TI - Global functional profiling of gene expression JO - Genomics VL - 81 UR - https://doi.org/10.1016/S0888-7543(02)00021-6 DO - 10.1016/S0888-7543(02)00021-6 ID - Draghici2003 ER - TY - JOUR AU - Manoli, T. AU - Gretz, N. AU - Grone, H. J. AU - Kenzelmann, M. AU - Eils, R. AU - Brors, B. PY - 2006 DA - 2006// TI - Group testing for pathway analysis improves comparability of different microarray datasets JO - Bioinformatics VL - 22 UR - https://doi.org/10.1093/bioinformatics/btl424 DO - 10.1093/bioinformatics/btl424 ID - Manoli2006 ER - TY - JOUR AU - Subramanian, A. AU - Tamayo, P. AU - Mootha, V. K. AU - Mukherjee, S. AU - Ebert, B. L. AU - Gillette, M. A. AU - Paulovich, A. AU - Pomeroy, S. L. AU - Golub, T. R. AU - Lander, E. S. PY - 2005 DA - 2005// TI - Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles JO - Proc Natl Acad Sci USA VL - 102 UR - https://doi.org/10.1073/pnas.0506580102 DO - 10.1073/pnas.0506580102 ID - Subramanian2005 ER - TY - JOUR AU - Barry, W. T. AU - Nobel, A. B. AU - Wright, F. A. PY - 2005 DA - 2005// TI - Significance analysis of functional categories in gene expression studies: a structured permutation approach JO - Bioinformatics VL - 21 UR - https://doi.org/10.1093/bioinformatics/bti260 DO - 10.1093/bioinformatics/bti260 ID - Barry2005 ER - TY - JOUR AU - Bolstad, B. M. AU - Irizarry, R. A. AU - Astrand, M. AU - Speed, T. P. PY - 2003 DA - 2003// TI - A comparison of normalization methods for high density oligonucleotide array data based on variance and bias JO - Bioinformatics VL - 19 UR - https://doi.org/10.1093/bioinformatics/19.2.185 DO - 10.1093/bioinformatics/19.2.185 ID - Bolstad2003 ER - TY - JOUR AU - Patel, S. AU - Lyons-Weiler, J. PY - 2004 DA - 2004// TI - caGEDA: a web application for the integrated analysis of global gene expression patterns in cancer JO - Appl Bioinformatics VL - 3 UR - https://doi.org/10.2165/00822942-200403010-00007 DO - 10.2165/00822942-200403010-00007 ID - Patel2004 ER - TY - JOUR AU - Huang da, W. AU - Sherman, B. T. AU - Tan, Q. AU - Collins, J. R. AU - Alvord, W. G. AU - Roayaei, J. AU - Stephens, R. AU - Baseler, M. W. AU - Lane, H. C. AU - Lempicki, R. A. PY - 2007 DA - 2007// TI - The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists JO - Genome Biol VL - 8 UR - https://doi.org/10.1186/gb-2007-8-9-r183 DO - 10.1186/gb-2007-8-9-r183 ID - Huang da2007 ER - TY - JOUR AU - Warburg, O. PY - 1925 DA - 1925// TI - Uber den Stoffwechsel der Carcinomzelle JO - Klin Wochenschr VL - 4 UR - https://doi.org/10.1007/BF01726151 DO - 10.1007/BF01726151 ID - Warburg1925 ER - TY - JOUR AU - Warburg, O. PY - 1956 DA - 1956// TI - On the origin of cancer cells JO - Science VL - 123 UR - https://doi.org/10.1126/science.123.3191.309 DO - 10.1126/science.123.3191.309 ID - Warburg1956 ER - TY - JOUR AU - Warburg, O. PY - 1956 DA - 1956// TI - On respiratory impairment in cancer cells JO - Science VL - 124 ID - Warburg1956 ER - TY - JOUR AU - Amuthan, G. AU - Biswas, G. AU - Ananadatheerthavarada, H. K. AU - Vijayasarathy, C. AU - Shephard, H. M. AU - Avadhani, N. G. PY - 2002 DA - 2002// TI - Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells JO - Oncogene VL - 21 UR - https://doi.org/10.1038/sj.onc.1205983 DO - 10.1038/sj.onc.1205983 ID - Amuthan2002 ER - TY - JOUR AU - Harris, M. H. AU - Vander Heiden, M. G. AU - Kron, S. J. AU - Thompson, C. B. PY - 2000 DA - 2000// TI - Role of oxidative phosphorylation in Bax toxicity JO - Mol Cell Biol VL - 20 UR - https://doi.org/10.1128/MCB.20.10.3590-3596.2000 DO - 10.1128/MCB.20.10.3590-3596.2000 ID - Harris2000 ER - TY - JOUR AU - Dey, R. AU - Moraes, C. T. PY - 2000 DA - 2000// TI - Lack of oxidative phosphorylation and low mitochondrial membrane potential decrease susceptibility to apoptosis and do not modulate the protective effect of Bcl-x(L) in osteosarcoma cells JO - J Biol Chem VL - 275 UR - https://doi.org/10.1074/jbc.275.10.7087 DO - 10.1074/jbc.275.10.7087 ID - Dey2000 ER - TY - JOUR AU - Gmeiner, W. H. AU - Hellmann, G. M. AU - Shen, P. PY - 2008 DA - 2008// TI - Tissue-dependent and -independent gene expression changes in metastatic colon cancer JO - Oncol Rep VL - 19 ID - Gmeiner2008 ER - TY - JOUR AU - Lin, H. M. AU - Chatterjee, A. AU - Lin, Y. H. AU - Anjomshoaa, A. AU - Fukuzawa, R. AU - McCall, J. L. AU - Reeve, A. E. PY - 2007 DA - 2007// TI - Genome wide expression profiling identifies genes associated with colorectal liver metastasis JO - Oncol Rep VL - 17 ID - Lin2007 ER - TY - JOUR AU - Cuezva, J. M. AU - Chen, G. AU - Alonso, A. M. AU - Isidoro, A. AU - Misek, D. E. AU - Hanash, S. M. AU - Beer, D. G. PY - 2004 DA - 2004// TI - The bioenergetic signature of lung adenocarcinomas is a molecular marker of cancer diagnosis and prognosis JO - Carcinogenesis VL - 25 UR - https://doi.org/10.1093/carcin/bgh113 DO - 10.1093/carcin/bgh113 ID - Cuezva2004 ER - TY - JOUR AU - Cuezva, J. M. AU - Krajewska, M. AU - de Heredia, M. L. AU - Krajewski, S. AU - Santamaria, G. AU - Kim, H. AU - Zapata, J. M. AU - Marusawa, H. AU - Chamorro, M. AU - Reed, J. C. PY - 2002 DA - 2002// TI - The bioenergetic signature of cancer: a marker of tumor progression JO - Cancer Res VL - 62 ID - Cuezva2002 ER - TY - JOUR AU - Airley, R. E. AU - Mobasheri, A. PY - 2007 DA - 2007// TI - Hypoxic regulation of glucose transport, anaerobic metabolism and angiogenesis in cancer: novel pathways and targets for anticancer therapeutics JO - Chemotherapy VL - 53 UR - https://doi.org/10.1159/000104457 DO - 10.1159/000104457 ID - Airley2007 ER - TY - CHAP AU - Cao, X. AU - Jia, G. AU - Zhang, T. AU - Yang, M. AU - Wang, B. AU - Wassenaar, P. A. AU - Cheng, H. AU - Knopp, M. V. AU - Sun, D. PY - 2008 DA - 2008// TI - Non-invasive MRI tumor imaging and synergistic anticancer effect of HSP90 inhibitor and glycolysis inhibitor in RIP1-Tag2 transgenic pancreatic tumor model BT - Cancer Chemother Pharmacol ID - Cao2008 ER - TY - JOUR AU - Duenas-Gonzalez, A. AU - Candelaria, M. AU - Perez-Plascencia, C. AU - Perez-Cardenas, E. AU - de la Cruz-Hernandez, E. AU - Herrera, L. A. PY - 2008 DA - 2008// TI - Valproic acid as epigenetic cancer drug: Preclinical, clinical and transcriptional effects on solid tumors JO - Cancer Treat Rev VL - 34 UR - https://doi.org/10.1016/j.ctrv.2007.11.003 DO - 10.1016/j.ctrv.2007.11.003 ID - Duenas-Gonzalez2008 ER - TY - JOUR AU - Hong, I. K. AU - Jin, Y. J. AU - Byun, H. J. AU - Jeoung, D. I. AU - Kim, Y. M. AU - Lee, H. PY - 2006 DA - 2006// TI - Homophilic interactions of Tetraspanin CD151 up-regulate motility and matrix metalloproteinase-9 expression of human melanoma cells through adhesion-dependent c-Jun activation signaling pathways JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.M601209200 DO - 10.1074/jbc.M601209200 ID - Hong2006 ER - TY - JOUR AU - Ang, J. AU - Lijovic, M. AU - Ashman, L. K. AU - Kan, K. AU - Frauman, A. G. PY - 2004 DA - 2004// TI - CD151 protein expression predicts the clinical outcome of low-grade primary prostate cancer better than histologic grading: a new prognostic indicator? JO - Cancer Epidemiol Biomarkers Prev VL - 13 ID - Ang2004 ER - TY - JOUR AU - Merajver, S. D. AU - Usmani, S. Z. PY - 2005 DA - 2005// TI - Multifaceted role of Rho proteins in angiogenesis JO - J Mammary Gland Biol Neoplasia VL - 10 UR - https://doi.org/10.1007/s10911-006-9002-8 DO - 10.1007/s10911-006-9002-8 ID - Merajver2005 ER - TY - JOUR AU - Wang, D. AU - Dou, K. AU - Xiang, H. AU - Song, Z. AU - Zhao, Q. AU - Chen, Y. AU - Li, Y. PY - 2007 DA - 2007// TI - Involvement of RhoA in progression of human hepatocellular carcinoma JO - J Gastroenterol Hepatol VL - 22 UR - https://doi.org/10.1111/j.1440-1746.2006.04534.x DO - 10.1111/j.1440-1746.2006.04534.x ID - Wang2007 ER - TY - JOUR AU - Takami, Y. AU - Higashi, M. AU - Kumagai, S. AU - Kuo, P. C. AU - Kawana, H. AU - Koda, K. AU - Miyazaki, M. AU - Harigaya, K. PY - 2008 DA - 2008// TI - The activity of RhoA is correlated with lymph node metastasis in human colorectal cancer JO - Dig Dis Sci VL - 53 UR - https://doi.org/10.1007/s10620-007-9887-0 DO - 10.1007/s10620-007-9887-0 ID - Takami2008 ER - TY - JOUR AU - Kamai, T. AU - Tsujii, T. AU - Arai, K. AU - Takagi, K. AU - Asami, H. AU - Ito, Y. AU - Oshima, H. PY - 2003 DA - 2003// TI - Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer JO - Clin Cancer Res VL - 9 ID - Kamai2003 ER - TY - JOUR AU - Chai, L. X. AU - Sun, K. L. AU - Guo, L. P. AU - Zhang, H. T. AU - Lu, S. X. PY - 2007 DA - 2007// TI - Expression of ezrin and CD44-v6 in human esophageal squamous cell carcinoma and its clinical significance JO - Zhonghua Zhong Liu Za Zhi VL - 29 ID - Chai2007 ER - TY - JOUR AU - Torer, N. AU - Kayaselcuk, F. AU - Nursal, T. Z. AU - Yildirim, S. AU - Tarim, A. AU - Noyan, T. AU - Karakayali, H. PY - 2007 DA - 2007// TI - Adhesion molecules as prognostic markers in pancreatic adenocarcinoma JO - J Surg Oncol VL - 96 UR - https://doi.org/10.1002/jso.20654 DO - 10.1002/jso.20654 ID - Torer2007 ER - TY - JOUR AU - Kobel, M. AU - Gradhand, E. AU - Zeng, K. AU - Schmitt, W. D. AU - Kriese, K. AU - Lantzsch, T. AU - Wolters, M. AU - Dittmer, J. AU - Strauss, H. G. AU - Thomssen, C. PY - 2006 DA - 2006// TI - Ezrin promotes ovarian carcinoma cell invasion and its retained expression predicts poor prognosis in ovarian carcinoma JO - Int J Gynecol Pathol VL - 25 UR - https://doi.org/10.1097/01.pgp.0000185410.39050.ac DO - 10.1097/01.pgp.0000185410.39050.ac ID - Kobel2006 ER - TY - JOUR AU - Yeh, T. S. AU - Tseng, J. H. AU - Liu, N. J. AU - Chen, T. C. AU - Jan, Y. Y. AU - Chen, M. F. PY - 2005 DA - 2005// TI - Significance of cellular distribution of ezrin in pancreatic cystic neoplasms and ductal adenocarcinoma JO - Arch Surg VL - 140 UR - https://doi.org/10.1001/archsurg.140.12.1184 DO - 10.1001/archsurg.140.12.1184 ID - Yeh2005 ER - TY - JOUR AU - Weng, W. H. AU - Ahlen, J. AU - Astrom, K. AU - Lui, W. O. AU - Larsson, C. PY - 2005 DA - 2005// TI - Prognostic impact of immunohistochemical expression of ezrin in highly malignant soft tissue sarcomas JO - Clin Cancer Res VL - 11 UR - https://doi.org/10.1158/1078-0432.CCR-05-0548 DO - 10.1158/1078-0432.CCR-05-0548 ID - Weng2005 ER - TY - JOUR AU - Khanna, C. AU - Wan, X. AU - Bose, S. AU - Cassaday, R. AU - Olomu, O. AU - Mendoza, A. AU - Yeung, C. AU - Gorlick, R. AU - Hewitt, S. M. AU - Helman, L. J. PY - 2004 DA - 2004// TI - The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis JO - Nat Med VL - 10 UR - https://doi.org/10.1038/nm982 DO - 10.1038/nm982 ID - Khanna2004 ER - TY - CHAP AU - Kelley, L. C. AU - Shahab, S. AU - Weed, S. A. PY - 2008 DA - 2008// TI - Actin cytoskeletal mediators of motility and invasion amplified and overexpressed in head and neck cancer BT - Clin Exp Metastasis ID - Kelley2008 ER - TY - JOUR AU - Mandal, M. AU - Myers, J. N. AU - Lippman, S. M. AU - Johnson, F. M. AU - Williams, M. D. AU - Rayala, S. AU - Ohshiro, K. AU - Rosenthal, D. I. AU - Weber, R. S. AU - Gallick, G. E. PY - 2008 DA - 2008// TI - Epithelial to mesenchymal transition in head and neck squamous carcinoma: association of Src activation with E-cadherin down-regulation, vimentin expression, and aggressive tumor features JO - Cancer VL - 112 UR - https://doi.org/10.1002/cncr.23410 DO - 10.1002/cncr.23410 ID - Mandal2008 ER - TY - JOUR AU - Xue, F. AU - Zhang, J. J. AU - Qiu, F. AU - Zhang, M. AU - Chen, X. S. AU - Li, Q. G. AU - Han, L. Z. AU - Xi, Z. F. AU - Xia, Q. PY - 7632 DA - 7632// TI - Rho signaling inhibitor, Y-2 inhibits invasiveness of metastastic hepatocellular carcinoma in a mouse model JO - Chin Med J (Engl) VL - 120 ID - Xue7632 ER - TY - JOUR AU - Evelyn, C. R. AU - Wade, S. M. AU - Wang, Q. AU - Wu, M. AU - Iniguez-Lluhi, J. A. AU - Merajver, S. D. AU - Neubig, R. R. PY - 2007 DA - 2007// TI - CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling JO - Mol Cancer Ther VL - 6 UR - https://doi.org/10.1158/1535-7163.MCT-06-0782 DO - 10.1158/1535-7163.MCT-06-0782 ID - Evelyn2007 ER - TY - JOUR AU - Wan, X. AU - Mendoza, A. AU - Khanna, C. AU - Helman, L. J. PY - 2005 DA - 2005// TI - Rapamycin inhibits ezrin-mediated metastatic behavior in a murine model of osteosarcoma JO - Cancer Res VL - 65 UR - https://doi.org/10.1158/0008-5472.CAN-04-3135 DO - 10.1158/0008-5472.CAN-04-3135 ID - Wan2005 ER - TY - JOUR AU - Khan, A. N. AU - Magner, W. J. AU - Tomasi, T. B. PY - 2007 DA - 2007// TI - An epigenetic vaccine model active in the prevention and treatment of melanoma JO - J Transl Med VL - 5 UR - https://doi.org/10.1186/1479-5876-5-64 DO - 10.1186/1479-5876-5-64 ID - Khan2007 ER - TY - JOUR AU - Khan, A. N. AU - Gregorie, C. J. AU - Tomasi, T. B. PY - 2008 DA - 2008// TI - Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes and MHC class I antigen presentation by melanoma cells JO - Cancer Immunol Immunother VL - 57 UR - https://doi.org/10.1007/s00262-007-0402-4 DO - 10.1007/s00262-007-0402-4 ID - Khan2008 ER - TY - JOUR AU - Manning, J. AU - Indrova, M. AU - Lubyova, B. AU - Pribylova, H. AU - Bieblova, J. AU - Hejnar, J. AU - Simova, J. AU - Jandlova, T. AU - Bubenik, J. AU - Reinis, M. PY - 2008 DA - 2008// TI - Induction of MHC class I molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-associated tumours JO - Immunology VL - 123 ID - Manning2008 ER - TY - JOUR AU - Benjamini YaH, Y. PY - 1995 DA - 1995// TI - Controlling the false discovery rate: a practical and powerful approach to multiple testing JO - J Roy Stat Soc B VL - 57 ID - Benjamini YaH1995 ER - TY - JOUR AU - Storey, J. D. AU - Tibshirani, R. PY - 2003 DA - 2003// TI - Statistical methods for identifying differentially expressed genes in DNA microarrays JO - Methods Mol Biol VL - 224 ID - Storey2003 ER - TY - CHAP AU - Adrian Mondry, M. L. AU - Alessandro, G. i. u. l. i. a. n. i. PY - 2007 DA - 2007// TI - DNA expression microarrays may be the wrong tool to identify biological pathways BT - Nature Preceedings ID - Adrian Mondry2007 ER - TY - JOUR AU - Tong, W. AU - Cao, X. AU - Harris, S. AU - Sun, H. AU - Fang, H. AU - Fuscoe, J. AU - Harris, A. AU - Hong, H. AU - Xie, Q. AU - Perkins, R. PY - 2003 DA - 2003// TI - ArrayTrack – supporting toxicogenomic research at the U.S. Food and Drug Administration National Center for Toxicological Research JO - Environ Health Perspect VL - 111 UR - https://doi.org/10.1289/ehp.6497 DO - 10.1289/ehp.6497 ID - Tong2003 ER -