Table 1 Top ten pathways ranked by PRS (T2D and pancreatic islets dataset)
From: A MATLAB tool for pathway enrichment using a topology-based pathway regulation score
Rank | Pathway name | PRS | pvalue | FDR |
|---|---|---|---|---|
1 | Arachidonic acid metabolism | 3.450412 | 0 | 0 |
2 | Cytokine-cytokine receptor interaction | 1.443531 | 0 | 0 |
3 | TGF-beta signalling pathway | 1.345376 | 0 | 0 |
4 | Complement and coagulation cascades | 1.180362 | 0 | 0 |
5 | PPAR signaling pathway | 1.030316 | 0.002 | 0.0065 |
6 | Pathways in cancer | 0.910555 | 0.004 | 0.0104 |
7 | Type II diabetes mellitus | 0.793327 | 0.002 | 0.0065 |
8 | Tryptophan metabolism | 0.754089 | 0.001 | 0.004875 |
9 | MAPK signaling pathway | 0.736616 | 0.001 | 0.004875 |
10 | Fatty acid metabolism | 0.701842 | 0.004 | 0.0104 |