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Table 2 Top ten pathways ranked by Z-score (T2D and pancreatic islets dataset)

From: A MATLAB tool for pathway enrichment using a topology-based pathway regulation score

Rank

Pathway

Z-score

1

Arachidonic acid metabolism

6.103672

2

TGF-beta signaling pathway

5.571651

3

Complement and coagulation cascades

5.468563

4

PPAR signaling pathway

5.302763

5

Cytokine-cytokine receptor interaction

5.102405

6

Fatty acid metabolism

5.050608

7

Intestinal immune network for IgA production

4.748036

8

Cell adhesion molecules (CAMs)

4.601507

9

Allograft rejection

4.480696

10

Staphylococcus aureus infection

4.416682