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Table 1 Top-25 age-associated genes with increased expression level (Van den Akker et al. [19])

From: A fast algorithm for determining bounds and accurate approximate p-values of the rank product statistic for replicate experiments

Symbol GeneID ρ    p -value   
    Exact Gamma Upper bound Geometric mean Lower bound
GPR56 9289 9282 2.645 × 10-10 5.255 × 10-09 3.888 × 10-10 2.709 × 10-10 1.887 × 10-10
HF1 3075 48576 2.074 × 10-09 2.296 × 10-08 2.873 × 10-09 2.117 × 10-09 1.559 × 10-09
SYT11 23208 57600 2.550 × 10-09 2.671 × 10-08 3.510 × 10-09 2.601 × 10-09 1.927 × 10-09
ARP10 164668 179400 9.817 × 10-09 7.297 × 10-08 1.303 × 10-08 1.000 × 10-08 7.680 × 10-09
B3GAT1(CD57) 27087 278460 1.635 × 10-08 1.075 × 10-07 2.142 × 10-08 1.666 × 10-08 1.295 × 10-08
SLC1A7 6512 483780 3.078 × 10-08 1.746 × 10-07 3.970 × 10-08 3.135 × 10-08 2.476 × 10-08
IFNG 3458 1594440 1.171 × 10-07 4.953 × 10-07 1.465 × 10-07 1.192 × 10-07 9.697 × 10-08
DSCR1L1 10231 2004864 1.507 × 10-07 6.046 × 10-07 1.874 × 10-07 1.533 × 10-07 1.254 × 10-07
ARK5 9891 2726880 2.110 × 10-07 7.898 × 10-07 2.605 × 10-07 2.146 × 10-07 1.768 × 10-07
PIG13 81563 3549314 2.809 × 10-07 9.927 × 10-07 3.448 × 10-07 2.857 × 10-07 2.367 × 10-07
SPUVE 11098 3880576 3.093 × 10-07 1.072 × 10-06 3.789 × 10-07 3.146 × 10-07 2.612 × 10-07
PDGFRB 5159 4294368 3.451 × 10-07 1.171 × 10-06 4.217 × 10-07 3.509 × 10-07 2.920 × 10-07
EDG8 53637 5083584 4.137 × 10-07 1.355 × 10-06 5.037 × 10-07 4.207 × 10-07 3.513 × 10-07
MARLIN1 152789 5505984 4.507 × 10-07 1.451 × 10-06 5.477 × 10-07 4.582 × 10-07 3.833 × 10-07
TGFBR3 7049 8081700 6.784 × 10-07 2.021 × 10-06 8.176 × 10-07 6.896 × 10-07 5.815 × 10-07
GZMB 3002 9886240 8.396 × 10-07 2.404 × 10-06 1.008 × 10-06 8.533 × 10-07 7.227 × 10-07
DEFA3 1168 9980528 8.481 × 10-07 2.423 × 10-06 1.018 × 10-06 8.619 × 10-07 7.301 × 10-07
KRT1 3848 11787930 1.010 × 10-06 2.796 × 10-06 1.208 × 10-06 1.027 × 10-06 8.728 × 10-07
CX3CR1 1524 12060288 1.035 × 10-06 2.851 × 10-06 1.237 × 10-06 1.052 × 10-06 8.944 × 10-07
STYK1 55359 14337372 1.241 × 10-06 3.308 × 10-06 1.477 × 10-06 1.260 × 10-06 1.076 × 10-06
ADRB2 154 16272900 1.416 × 10-06 3.687 × 10-06 1.681 × 10-06 1.438 × 10-06 1.231 × 10-06
GAF1 26056 35217600 3.138 × 10-06 7.128 × 10-06 3.667 × 10-06 3.186 × 10-06 2.769 × 10-06
CTSL 1514 38246400 3.414 × 10-06 7.647 × 10-06 3.982 × 10-06 3.465 × 10-06 3.016 × 10-06
GFI1 2672 56960480 5.107 × 10-06 1.072 × 10-05 5.907 × 10-06 5.183 × 10-06 4.547 × 10-06
TTC38 55020 59340600 5.322 × 10-06 1.110 × 10-05 6.150 × 10-06 5.400 × 10-06 4.742 × 10-06