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Table 2 Number of genes called significant according to Bonferroni correction and FDR q -values

From: A fast algorithm for determining bounds and accurate approximate p-values of the rank product statistic for replicate experiments

 

Bonferroni correction

 

q -value

 
  

< 0.001

< 0.01

< 0.05

Up-regulated genes

    

Exact

25

   

Gamma

21

14

40

112

Upper bound

23

21

57

122

Geometric mean

25

21

58

129

Lower bound

26

21

59

131

Down-regulated genes

Exact

42

   

Gamma

30

23

69

140

Upper bound

42

39

74

143

Geometric mean

42

42

74

154

Lower bound

43

43

75

157

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BMC Bioinformatics

ISSN: 1471-2105

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