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Table 3 The number of true-positives and false-negatives in indel verification by Sanger sequencing for no quality control vs. trimming vs. masking

From: Masking as an effective quality control method for next-generation sequencing data analysis

Aligners No quality control Trimming Masking
True- positive False- negative True- positive False- negative True- positive False- negative
BWA 20 2 20 2 20 2
BOWTIE2 20 2 20 2 20 2