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Table 5 Overlap of co-purifying proteins identified through LGTS-MS with previously reported (known) interactions and MP-PIPE predictions

From: Efficient prediction of human protein-protein interactions at a global scale

 

Reachable proteins

Prey reached

Recall 1

Precision 2

Bait

# of prey

Known

MP-PIPE

Known

MP-PIPE

Known

MP-PIPE

Known

MP-PIPE

Q09028

301

112

201

56

99

18.60%

32.89%

50.00%

49.25%

P83916

474

91

244

59

178

12.45%

37.55%

64.84%

72.95%

P16104

209

39

207

11

82

5.26%

39.23%

28.21%

39.61%

Q99496

292

16

24

13

15

4.45%

5.14%

81.25%

62.50%

Total

1276

258

676

139

374

10.89%

29.31%

53.88%

55.33%

  1. 1Recall calculated as reached/# of prey.
  2. 2Precision calculated as reached/reachable.