Figure 1
From: SPoRE: a mathematical model to predict double strand breaks and axis protein sites in meiosis
Summary of SPoRE modeling approach. Two main steps constitute the approach and they are described from top to bottom (center). First, SPoRE considers a set of positions to which it assigns weights. Axis proteins (red) and DSBs (blue) involve convergent genes and divergent genes, respectively. In the drawing, locations with non-zero weight are indicated by colored vertical bars (height represents importance) and triangles: convergent genes for axis proteins and divergent regions for DSBs display the highest weights (top). Then, SPoRE smooths the distribution of weights with a Gaussian kernel (bottom) modeling, in this way, the diffusion of the proteins around their main sites. The red box on the left (A; axis proteins) and the blue box on the right (B; DSB) describe some details of SPoRE models.