Figure 1
Results of ChrX eQTL meta-analysis in Liver: cis-regulation of DUSP9. Significance of association between genotype variants and DUSP9 expression. Position (in Mb) on the horizontal axis; −log10(pvalue) on the vertical axis. Top panel: associations in females; middle panel: associations in males; bottom panel: meta-analysis results. Highlighted in gray the position of DUSP9 on the genome. Although some evidence of cis-regulation of DUSP9 is already observed in males and females separately, the meta-analysis of the two datasets provides a sharper and more conclusive signal.