Meta-eQTL: a tool set for flexible eQTL meta-analysis

BMC Bioinformatics

Table 3 eQTL statistics on ChrX diabetes GWAS hits

eQTL Gene	eSNP rsID*	eQTL Eff Allele	eQTL pvalue	β	T meta	T male	T female	eQTL Type	Tissue
F8	rs2664170	A	3.8E-07	−3.60	−5.08	−2.93	−4.26	cis	Liver
AK095886	rs2664170	A	9.6E-04	−2.36	−3.30	−0.93	−3.43	cis	Liver
CTAG2	rs2664170	A	1.2E-03	2.35	3.25	0.69	3.46	cis	Liver
IKBKG	rs2664170	A	7.4E-03	1.92	2.68	1.07	2.53	cis	Liver
CTAG1B	rs2664170	A	8.7E-03	1.88	2.62	1.35	2.27	cis	Liver
AK095886	rs2664170	A	7.0E-07	−3.56	−4.96	−2.56	−4.34	cis	Omental
IKBKG	rs2664170	A	5.1E-05	2.90	4.05	2.48	3.26	cis	Omental
F8A1	rs2664170	A	2.4E-04	−2.61	−3.67	−1.53	−3.52	cis	Omental
SLC10A3	rs2664170	A	2.7E-04	2.59	3.64	2.99	2.30	cis	Omental
AK095886	rs2664170	A	8.1E-07	−3.52	−4.93	−2.88	−4.10	cis	SubQ
IKBKG	rs2664170	A	5.5E-04	2.45	3.46	3.35	1.77	cis	SubQ
Contig21200_RC	rs2664170	A	4.3E-08	−3.91	−5.48	−2.69	−4.96	trans	SubQ
XM_210086	rs5945326	A	7.0E-03	1.94	2.70	0.61	2.86	cis	Liver
SLC6A8	rs12010175	G	2.8E-04	2.62	3.63	2.99	2.41	cis	Liver
ARHGAP4	rs12010175	G	8.2E-03	1.91	2.64	0.13	3.08	cis	Liver
BC030106	rs12010175	G	1.8E-03	2.28	3.12	2.81	2.00	cis	Omental
HSS00085101	rs12010175	G	3.2E-03	−2.11	−2.94	−1.15	−2.82	cis	Omental
PLXNB3	rs12010175	G	3.0E-04	2.62	3.61	1.42	3.41	cis	SubQ
BC030106	rs12010175	G	7.6E-04	2.38	3.37	2.07	2.71	cis	SubQ

*SNPs rs2664170, rs5945326 and rs12010175 were identified as eQTL, and these SNPs are also reported in association with diabetes by large GWA studies (summarized in Table 2).

ISSN: 1471-2105