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Figure 2 | BMC Bioinformatics

Figure 2

From: Improving statistical inference on pathogen densities estimated by quantitative molecular methods: malaria gametocytaemia as a case study

Figure 2

Calibration or standard curves derived from individual quantitative nucleic acid sequence-based amplification (QT-NASBA) assays. Panels depict data and fitted calibration curves for assays j = 1,2,…,12. Solid and broken lines denote medians and 95% Bayesian credible intervals (BCIs) of the posterior predictive distribution of time to positivity (TTP) calculated from the heteroscedastic linear mixed model (HeLMM) and the homoscedastic linear model (HoLM) respectively (note that for the HoLM these are identical to classical frequentist prediction intervals). Dark and light grey lines correspond to, respectively, BCIs for m = 1 TTP observation and the mean of m = 3 TTP observations.

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