Figure 5
Sensitivity and consistency of detecting Plasmodium falciparum gametocytes by quantitative nucleic acid sequence-based amplification (QT-NASBA). The boxes surrounded by dashed lines depict, respectively, the distribution of assay-specific sensitivities derived from the 12 individually-fitted homoscedastic liner models (HoLMs) and the heteroscedastic linear mixed model (HeLMM). Boxes span from the 25th to the 75th percentiles (the interquartile range) of the estimated sensitivities and whiskers a further 1.5 × the interquartile range. Points outside of this range are indicated and horizontal bars (broken and solid) indicate medians. Boxes shaded dark grey and light grey correspond to, respectively, estimates derived from a single time to positivity (TTP) observation (m = 1) or the mean of 3 TTP observations (m = 3).