Figure 5
From: An integrated network visualization framework towards metabolic engineering applications
Visualization of parts of the iJR904 model layout representing the main genetic modifications performed over the model to produce succinate. A part of the central metabolism; B inactivation of the pyridine nucleotide transhydrogenase (R_THD2); C deletion of Transketolase I; D inactivation of the succinate dehydrogenase (R_SUCDli), in the TCA-cycle; E knockout of serine hydroxyl methyltransferase reaction (R_GHMT2).