ROC curve. Receiver operator characteristic curves for ONCOCNV (o) and our own development using the comparison dataset (Table 2): Plain t-test statistics without corrections (naive, n) compared to the performance achieved by using weights (w) or removing outliers (r). The final algorithm quandico (q) includes both of these steps together with an additional dispersion balancing. Symbols are plotted for local maxima. The inset shows a magnification of the region above 90% specificity and sensitivity.