-mer counts associated with an Illumina MiSeq read containing two highlighted substitution errors. The k-mers are of length 31. A data point corresponds to the number of times a left-anchored k-mer, starting at a given position within the sequence, has been observed in the entire read set. The first error is located near the middle of the read and affects the counts associated with 31 k-mers. The second error located only four positions in from the 3’ end of the read and affects only 4 k-mer counts.