Figure 3From: Rational selection of experimental readout and intervention sites for reducing uncertainties in computational model predictions Experimental design: inhibition and readout selection for best parameter estimation. (a) Criterion space for all 6 possible single inhibition scenarios. An inhibition of a specific reaction is simulated by reducing the corresponding kinetic parameters by a factor of 10−4. (b) Profile likelihoods for different readout and inhibition scenarios (indicated by the gray arrows).Back to article page