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Table 2 Comparison of a) unguided fixed-height cuts; b) guided fixed-height cuts; c) unguided piecewise snipping; d) guided piecewise snipping; e) guided piecewise snipping + PNNC

From: Semi-supervised adaptive-height snipping of the hierarchical clustering tree

Data

Fixed-height cut

Piecewise snipping

 

Unguided

Guided

Unguided

Guided

Guided

 
 

Ward

Ward

Ward

Ward

PNNC

Global test

Lung.1

0.394

0.167

0.308

0.071

0.016

0.019

Leukemia

0.688

0.238

0.336

0.016

0.002

0.004

Lung.2

0.256

0.497

0.418

0.103

0.048

0.227

Lymphoma

0.149

0.113

0.176

0.038

0.001

0.001

Prostate

0.086

0.360

0.091

0.083

0.107

0.002

Glioblastoma

0.142

0.160

0.064

0.041

0.103

0.003

  1. All guided approaches use WSS + AIC as cluster evaluation criterion, the unguided approaches use WSS only; a)-d) use Ward distance for test sample assignment, whereas e) uses PNNC. The first five numeric columns contain the median log-rank p-values across the three splits of the 3-fold CV. The last column contains the p-values from the global test for overall association between the molecular and time-to-event data.
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BMC Bioinformatics

ISSN: 1471-2105

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