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Table 2 Comparison of a) unguided fixed-height cuts; b) guided fixed-height cuts; c) unguided piecewise snipping; d) guided piecewise snipping; e) guided piecewise snipping + PNNC

From: Semi-supervised adaptive-height snipping of the hierarchical clustering tree

Data Fixed-height cut Piecewise snipping
  Unguided Guided Unguided Guided Guided  
  Ward Ward Ward Ward PNNC Global test
Lung.1 0.394 0.167 0.308 0.071 0.016 0.019
Leukemia 0.688 0.238 0.336 0.016 0.002 0.004
Lung.2 0.256 0.497 0.418 0.103 0.048 0.227
Lymphoma 0.149 0.113 0.176 0.038 0.001 0.001
Prostate 0.086 0.360 0.091 0.083 0.107 0.002
Glioblastoma 0.142 0.160 0.064 0.041 0.103 0.003
  1. All guided approaches use WSS + AIC as cluster evaluation criterion, the unguided approaches use WSS only; a)-d) use Ward distance for test sample assignment, whereas e) uses PNNC. The first five numeric columns contain the median log-rank p-values across the three splits of the 3-fold CV. The last column contains the p-values from the global test for overall association between the molecular and time-to-event data.