Figure 4

Kinetics around CCG repeats. These three graphs show the average polymerase kinetics for the sequence CCGCCGCCGCC, found in 27 regions in the E. coli genome. A total of 1222 reads were used in the analysis. The top graph shows the raw IPD values for the region, in seconds. In the middle and bottom graphs, the 2 bp (4 bp) smoothing represents wavelet smoothing over a two (four) nucleotide region within the reads. For each measurement, the black vertical lines are the 90% quantile, the grey vertical lines are the 95% quantile. Note that the scale here is much smaller than that of the previous figure.